Find out more about how Glatt, as a plant manufacturer and expert in technologies and processes for particle design, is meeting the current requirements from the powder processing industry. In their presentation “Trends and challenges in fluid bed encapsulation processes”, Katja Oppermann and Didier Schons, both Glatt Ingenieurtechnik, will explain which options are opened up by adapted technological concepts.
Free-flowing granules and pellets from liquids and powders using innovative fluid bed and spouted bed technology at Booth G12 in Hall 1. With state-of-the-art fluid bed and spouted bed technologies, Glatt offers intelligent particle design to dry, shape and functionalize powders and granules with the desired properties in just one process step, improving their application and handling.
On 1 March 2022, Glatt Ingenieurtechnik GmbH opened a new branch in Cologne. The new unit will showcase the company’s pharmaceutical, biotechnology and active ingredient plant expertise and represents Glatt’s first location in North Rhine-Westphalia. The decision to expand was based on a positive market outlook in the field of pharmaceutical engineering and excellent capacity utilization.
In January 2022, plant manufacturer and process expert, Glatt Ingenieurtechnik, expanded its powder synthesis capacity at the company’s technology center in Weimar. The newly installed system ensures a homogenous process temperature throughout the entire length of the ProAPP® 80 HT reactor or the targeted adjustment of temperature gradients. This allows different process steps to be combined.
Weimar, Germany, March 2022: Glatt Ingenieurtechnik GmbH (Weimar, Germany) will be responsible for the Basic Engineering of the process technology for the multipurpose BioCampus MultiPilot (BMP) plant on behalf of BioCampus Straubing GmbH. Here, at the Straubing-Sand port, customers will be able to develop, test, optimize and scale-up industrial biotechnology processes, validate their economic viability and manufacture samples.
SaMBa research project for a novel fabrication process for high permeability oxygen membranes and development of an innovative membrane connection plate for oxygen generators: “Mixed ionic electronic conductor” (MIEC) Membranes are specialized single phase materials which exhibit significant electron and ionic conductivity. Neutral molecules can be transported through a solid membrane and separated from other components. BSCF (barium-strontium-cobalt-iron oxide) enables oxygen exchange. Research focuses on the production of BSCF by Glatt powder synthesis and the subsequent production of the membranes for oxygen separation from air.
Elaboration of the plant and control engineering fundamentals for the precise control of particle growth in granulation processes. From this, reliable statements on the industrial scalability and pharmaceutical suitability of self-regulating granulation processes can be derived. The results create the technological prerequisites for a completely new quality level in the manufacture of pharmaceutical products (granules and tablets).
Powdery substances often cause problems during dosing, filling and transport because of their high dust content and poor flowability. Low solubilities and dispersing properties also impair the application of the end product. With the help of fluidised bed spray agglomeration, the size distribution and structure of difficult-to-process particles can be specifically adjusted and improved.
The poster reports a case study involving the spray granulation of a solution using continuous fluidized bed and spouted processing.
Based on various experiments in laboratory and pilot scale a statistical process model was derived based on artificial neural networks. A parameter study and sensitivity analysis was performed to determine the main process conditions and formulation variables. The multi-dimensional model of the process supported the optimization of product properties (e.g. particle size, particle sphericity) and related process conditions (e.g. product temperature, spray rate).
Glatt technologies are usable to add value or improve product properties of dry detergent formulations. Liquids or powders can be processed to innovative products. Benefits of technology. Fluidized and spouted bed equipment. Strategy for product and process development. Case study »Homogeneity of mixture«. Case study »Chemical reaction and granulation«. Case study »Granulation of polymers or surfactants«. Case study »Coated enzyme granules«.
Copyright by Glatt
Copyright: Glatt
Copyright: Glatt