Fluidic simulation helps to design and optimize fluid bed spray granulators: Starting from a basis technology, project-specific special purpose machines are developed. Classical development steps such as prototype manufacture are no longer practicable. Advanced methods and tools have to be used to minimize the financial and material risk in the project phase. Among other things fluidic simulation is used here to develop fluid bed machines in a more efficient manner and to implement knowledge from pilot-scale experiments to a large scale.