Film Coating, Lipid Coating, Hotmelt Coating
Spray coating in the fluidized bed or spouted bed.
Functionalization of particle surfaces.
Sensory attractiveness.
Protective mechanisms.
Release control.
Targeted influencing of the surface structure of particles through the application of functional coatings.
Spray coating – film coating, lipid coating or hot melt coating – in the fluid bed and spouted bed is an effective process for applying protective films and functional layers, for example to increase shelf life or storage stability. Colored brandings can be realized as well as the enhancement of sensory attractiveness, for example for odor and taste masking. Particle properties such as those for retardation or controlled release can also be specifically influenced by means of film coating, lipid coating or hot melt coating.
It is important to apply the coating material very uniformly. Application and solidification take place in a single system. The film material is applied from a solution, a suspension or as a melt. The specific choice of process parameters prevents the formation of liquid bridges and avoids undesirable agglomeration during film application.
Particles of different shapes and sizes can be moved in the fluid bed or spouted bed and sprayed with liquids in the process. Particles and granules previously produced by spray granulation, agglomeration, active material layering or spray drying can be additionally functionalized by spray coating. Typical particle sizes are 100 micrometers to 3 millimeters.
Film coating, lipid coating or hot melt coating processes in fluid bed systems and spouted bed systems can be carried out in batch operation or in a continuous process.
For protective coatings and new functions for micro- and nanopowders, Glatt offers core-shell coating in the pulsating gas stream of Glatt powder synthesis.
These product properties can be specifically influenced by means of film coating, lipid coating or hot melt coating in the fluid bed or spouted bed:
Active
Ingredient Release
Odor and
Taste
Shelf-life /
Storability
Optical
Attractiveness
Surfaces
Structure
Light / UV
Sensitivity
Solubility
Flow Behavior
Sorption Behavior /
Hygroscopicity
Thermal
Stability
Chemical
Compatibility
Oxidation
Stability
Mechanical
Strength
Retardation /
Resolution Delay
Multilayer Coating for Staggered Functionality
Typical particle sizes are 100 micrometers to 3 millimeters.
Wide range of variants
Coating layers can be realized in different ways, depending on the requirements for the product properties.
Film coating is a very effective process for applying ultra-thin, functional barrier, protective and color layers or other functional coatings. When coating from a solution or suspension, the liquid serves to transport the solid onto the surface of the particles. The aqueous or organic solvent evaporates, and the solid contained in it forms the coating layer.
- low mass fraction of the functional layer in relation to the particle core provided
- layer thicknesses between approx. 5 and 50 micrometers (and more)
Lipid coating as well as hot melt coating are very effective processes for coating or encapsulating particles by applying melts and creating solid protective films for influencing particle properties by solidification.
- fast film application
- no solvent evaporation necessary
- small to large coating masses in relation to the particle applied
- layer thicknesses between approx. 25 µm and several 100 µm
- dense release layers with multilayer build-up
In hotmelt coating, the melt to be applied consists one hundred percent of coating material in a spreadable state. The particle shell is formed here by solidification of the sprayed-on melt. Well suited for rapid coating application. The use of melts as coating liquid also eliminates the energy-intensive evaporation of solvents.
For coating very finely divided or irregularly structured particles, spouted bed coating or fluid bed HS Wurster coating is suitable.
Copyright by Glatt
Copyright: Glatt