Lysine, spray granulation in the fluid bed
Benefit from the numerous advantages by drying liquids into powder or granules
Spray drying of liquid products has always been used because of its many advantages. In addition to the significantly longer storage stability of powders and the fact that no cooling is required, the transport volume is reduced many times over compared to liquids. Contamination through leakage or after transport accidents is difficult to prevent with liquids. Where liquids easily find their way, powders remain more localized and do not penetrate the soil.
Better solubility and pourability, dust-free and reduced explosion risk through agglomeration of fine powders
For this reason, most industries use large spray towers and efficiently dry large volumes of liquid into powders. The small particle size of these powders causes problems in handling due to dust formation and, associated with this, an increased explosion risk with organic products. In many cases, additional agglomeration is added downstream. This causes an increase in particle size and improves the flowability. Agglomerates from spray tower powders are characterized by a very low bulk density. This is due to vacuoles that are formed during the extremely fast drying process. However, a lower bulk density subsequently results in poorer sinking behavior and poorer solubility. These properties can be optimized by changing the process.
Granules directly from the liquid and even more influence on product parameters by spray granulation
The spray granulation process based on fluid bed technology offers decisive advantages in this respect. The spray liquid is only dried to a limited extent to form primary particles, but is also used as a binder for agglomeration in the continuous process. Essential for the solubility are the particle size and the particle structure. Fine particles with a particle size of a few 100 micrometers require a sufficiently large weight to sink in quickly. Solubility is determined by the capillaries of the agglomerates that allow the liquid to penetrate. Spray granulation in a continuously operating fluid bed apparatus passes through several process chambers. Different process conditions can be set in each of these chambers. In this way, very defined granule properties can be achieved in a single process. In addition to porous, highly soluble products, the particle structures can also be shifted in the direction of compact and abrasion-resistant. Hygroscopic products then benefit from the smaller surface area and have less tendency to stick. Allergens are firmly bound and can be handled safely. Furthermore, granules with a compact uniform structure are also suitable for additional functionalization through a coating. From protective coating to controlled release, many options are conceivable.
Develop and test your material at the Glatt Technology Center in Weimar
We will be pleased to support you in the realization of your product innovations. At the Glatt Technology Center in Weimar, we work with you to determine the optimum process conditions for your product in feasibility trials for product development. Various laboratory facilities and comprehensive analytical equipment are available for this purpose. On our pilot plants, we optimize the process and scale it up reliably to a stable and economical production scale. The results from this form the basis for the design and construction as well as the erection of your plant, tailored to your requirements. As an alternative to our own process technology, we offer you the outsourcing of your production by means of contract manufacturing at Glatt.
Further information on this topic and related topics can also be found in the following publications: